Pseudohypoaldosteronism.
نویسندگان
چکیده
منابع مشابه
PSEUDOHYPOALDOSTERONISM: A CASE REPORT
A four day old female infant was admitted because of poor feeding, vomiting and jaundice. Laboratory examination showed hyperkalemia, mild hyponatremia and renal tubular acidosis type 4. Serum aldosterone and plasma renin activity were elevated but serum cortisol, 17 -hydroxyprogesterone, ACTH, 24 hour urinary 17- ketoste roid, pregnanetriol, renal function and sonogram were normal and henc...
متن کاملSporadic pseudohypoaldosteronism: A challenging diagnosis
Introduction: Pseudohypoaldosteronism (PHA) is a rare form of saltwasting syndrome, caused by peripheral resistance to aldosterone. PHA is of three types: PHA type 1, 2, 3. Pseudohypoaldosteronism type 1 (PHA1) is further differentiated into, (i) hereditary forms, autosomal recessive and dominant, which are caused by epithelial sodium channel and mineralocorticoid receptor mutations respective...
متن کاملpseudohypoaldosteronism
- pseudohypoaldosteronism (p'ha) is referred to a state of endorgan unresponsiveness to aldosterone. in this article a 12 day - old mule newborn is presented with hyponatremia, hyperkalemia and metabolic acidosis. aldosterone level and plasma renin activity were high. mineralocorticoids had no therapeutic effect, hut normal saline infusion improved electrolyte imbalance. salt-rich diet was succ...
متن کاملDisturbances of Na/K balance: pseudohypoaldosteronism revisited.
Introduction Pseudohypoaldosteronism (PHA) is a heterogenous syndrome resulting from the inability for aldosterone to produce one of its physiologic effects, namely the promotion of potassium and hydrogen secretion. It is thus characterized by three essential features: (1) hyperkalemia, (2) metabolic acidosis, and (3) abnormally elevated plasma aldosterone concentrations. It has been classified...
متن کاملA molecular update on pseudohypoaldosteronism type II.
The DCT (distal convoluted tubule) is the site of microregulation of water reabsorption and ion handling in the kidneys, which is mainly under the control of aldosterone. Aldosterone binds to and activates mineralocorticoid receptors, which ultimately lead to increased sodium reabsorption in the distal part of the nephron. Impairment of mineralocorticoid signal transduction results in resistanc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1980
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.55.6.427